Oxford needed to win their home game against Leyton Orinet to avoid relegation, but Leyton Orient also needed to win to gain promotion to League One.
The game finished with Leyton Orient winning 3-2, so they have been promoted, and Oxford relegated into the Conference after over 40 years in the Football League.
Swindon may still have a local derby against Cheltenham, but only if they don't win the play off's, but the local derby against Bristol Rovers is the only confirmed derby next season so far.